Don't Get Your DNA In A Bind

If you’ve ever seen lab plastics advertised as “low binding” you might wonder what DNA binding is and why it’s such a problem. In short, it has been found that DNA can bind, or get stuck to the surface of some types of plastics, including polypropylene. This can have noticeable impacts on your test results, especially when it comes to low reaction volumes as in qPCR and NGS applications. Low DNA binding means more genetic material remains in suspension, and therefore is available for your chemical reaction or sample recovery after incubation.

While most PCR plates are manufactured with polypropylene reaction wells, some of the leading companies offer specialty, low binding PCR plates. We hired an independent company to measure DNA binding in Arvensis plates compared to the global market leaders to see what kind of difference these low binding plates can make. In summary, there was no difference found in DNA binding between Arvensis products and low binding products from leading brands. This is our commitment to quality and integrity: we only offer plates made of low binding plastic as an integral feature of our regular line of products; not as a specialty item, and certainly not at a higher price point.

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